Update on Applications in Bipolar Disorder

The authors investigate where CYP2C19 polymorphisms are associated with antidepressant treatment patterns and the risk of mania when antidepressants are used in bipolar disorder. " This is the first large scale study of the impact of CYP2C19 metabolic phenotypes on antidepressant treatment patterns and adverse events in bipolar disorder patients. We report largely negative results on antidepressant discontinuation and treatment "

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